Stimulant Overdose Symptoms and Care
What are Stimulants?
Stimulants are a class of drugs or substances that increase the activity of the central nervous system. They produce temporary changes in mental and physical functions. This often includes increased alertness and energy.1
Stimulants work by increasing the levels of certain neurotransmitters in the brain. This includes dopamine and norepinephrine, which play essential roles in regulating mood. This increased activity of neurotransmitters leads to the associated stimulating effects.2

Learn More About Ripple Ranch Recovery Center
Types of Stimulants
Caffeine
- Coffee
- Tea
- Many soft drinks
Amphetamines
Cocaine
Cocaine is a powerful stimulant derived from the coca plant. It’s illegal for recreational use due to its highly addictive and harmful effects.
Methamphetamine
MDMA (Ecstasy)
Nicotine
Effects of Stimulants
- Addiction
- Cardiovascular problems
- Anxiety
- Cognitive impairment
Stimulant Overdose Symptoms and Signs
- Increased heart rate and blood pressure
- Chest pain
- Hyperthermia (elevated body temperature)
- Agitation and restlessness
- Seizures
- Respiratory distress
- Profuse sweating
- Nausea and vomiting
- Confusion and hallucinations
- Stroke or heart attack
- Coma
How do Stimulant Overdose Symptoms Vary Based on the Type of Stimulant?
Amphetamines (e.g. Adderall, Ritalin)
- Increased heart rate and blood pressure
- Agitation and restlessness
- Confusion and delirium
- Muscle tremors or twitches
- Hyperthermia (elevated body temperature)
- Nausea and vomiting
- Hallucinations
- Seizures
Cocaine
- Chest pain or angina
- Irregular heart rhythm
- Severe anxiety and paranoia
- Profuse sweating
- Increased risk of heart attack and stroke
- Agitation and restlessness
- Hyperthermia
- Nausea and vomiting
Methamphetamine
- Extreme agitation and aggressiveness
- Hallucinations (auditory and visual)
- Severe chest pain
- Elevated blood pressure and heart rate
- Profuse sweating
- Tremors and muscle stiffness
- Hyperthermia
- Risk of seizures
- Stroke or heart attack
MDMA (Ecstasy)
- Increased heart rate and blood pressure
- Profuse sweating
- Hyponatremia (low sodium levels), which can lead to swelling of the brain
- Confusion and agitation
- Nausea and vomiting
- Dehydration
- Hallucinations
- Seizures
Physiological Effects of Stimulant Overdose
Cardiovascular Effects
Temperature Regulation
- Heatstroke
- Dehydration
- Potential damage to internal organs
Respiratory Effects
Neurological Effects
Gastrointestinal Effects
Nausea and vomiting are frequent physiological responses to stimulant overdose. These symptoms can lead to dehydration, which worsens the overall physiological stress on the body.
Muscular Effects
Metabolic Effects
Renal (Kidney) Effects
Hepatic (Liver) Effects
How the Mental and Psychological Stimulant Overdose Symptoms Manifest
- Agitation and restlessness
- Confusion and disorientation
- Hallucinations
- Delirium
- Paranoia and anxiety
- Mood swings
- Psychosis
- Aggressiveness
- Suicidal thoughts
Role of Underlying Health Conditions and Individual Factors on Stimulant Overdose Symptoms
Role of Underlying Health Conditions
Tolerance and Dose
Polydrug Use
Mental Health and Psychological Factors
Preexisting mental health conditions can influence a person’s susceptibility to psychological symptoms during a stimulant overdose. Conditions such as anxiety or psychosis may be worsened by stimulant use. This can result in more severe psychological symptoms.
A person’s mental state at the time of use, such as stress, anxiety, or impulsivity, can also play a role.
Age, Genetics, and Metabolism
Route of Administration
Pre-existing Conditions, Medications, and Environmental Factors
Stimulant Overdose Symptoms and Timeline
Immediate Effects (Minutes to Hours After Ingestion)
- An increased heart rate
- Elevated blood pressure
- Heightened alertness and energy
Acute Phase (Hours After Ingestion)
Psychological and Cognitive Symptoms (Hours to Days After Ingestion)
- Confusion
- Delirium
- Hallucinations
- Paranoia
- Anxiety
- Mood swings
Late Stages (Hours to Days After Ingestion)
What Immediate Actions Should Be Taken?
- Call 911
- Stay calm
- Ensure safety
- Monitor vital signs
- Do not leave them alone
- Do not give substances
- Reassure and comfort
- Provide information
- Prepare for first responders
- Follow medical advice
How are Stimulant Overdose Symptoms Diagnosed And Treated?
Diagnosis
- Clinical assessment
- Physical examination
- Lab tests
- ECG (electrocardiogram)
Treatment
- Stabilization
- Supportive care
- Monitoring
- Psychological support
- Treatment of complications
- Psychiatric assessment
- Follow-up care
Interventions Used to Address the Physical and Psychological Aspects of Overdose
Physical Aspects
- Stabilization
- Hydration
- Temperature management
- Monitoring
- ECG (electrocardiogram)
- Treatment of cardiovascular complications
Psychological Aspects
- Psychological support
- Sedation
- Psychiatric assessment
- Counseling and therapy
- Supportive environment

What Therapies are Used to Help Treat Stimulant Addiction?
- Behavioral therapies such as cognitive-behavioral therapy (CBT), contingency management, motivational enhancement therapy (MET), and the community reinforcement approach (CRA)
- 12-Step programs
- Individual and group counseling
- Family therapy
- Pharmacotherapy for managing withdrawal symptoms and related conditions
- Holistic therapies, such as mindfulness meditation, yoga, acupuncture, and art therapy
- Relapse prevention skills and strategies
Learn More About Stimulant Overdose Symptoms and Treatment at Ripple Ranch
Navigating stimulant addiction and overdose can be daunting. At Ripple Ranch, you won’t have to go through it alone.
At Ripple Ranch, our professional team is prepared to meet you at every step of your recovery journey. From substance use education to treatment programs, we offer several resources to help restore balance in your life.
To learn more about stimulant overdose symptoms or the programs available to you or your loved one, contact us today.